Communication between immune system and mycobiota impacts health and disease

Fungi are the organisms present universally in environment from ancient times. Being regarded as an essential part of human mycobiome either commensals or opportunistic pathogens they hold a spectacular place our lives. Mycobiome is growing field interest, but some questions still remain lurking like how fungi exactly modulate health and disease. Most studies focus on interactions immune system with bacterial viral community rather than highlighting communication mycobiota. Crosstalk between mycobiota have been found to be highly necessary for maintaining homeostasis, preventing susceptibility towards diseases, inducing tolerance, modulating microbial communities generating signal responses by interacting fungal molecular patterns. We latest advancement regarding relationship innate adaptive branches immunity mycobiota, their role ranging simple more importantly therapies designed overcome infections this review.